C O N V I T E

A Coordenação do Programa de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos tem a satisfação de convidá-los para a palestra intitulada:

"Potencial farmacológico de carotenóides para aplicações em câncer" 

*A palestra é fruto de uma orientação em Cotutela no âmbito do Programa CAPES/PRINT e uma parceria da UFPB com a Universidade de La Rochelle-França.

PALESTRANTE: Prof. Dr. Laurente Picot

 

DATA: 26/11/2020 (quinta-feira)
HORÁRIO: 10:00h

IDIOMA: Inglês

LINK PARA VIDEOCONFERÊNCIA: será enviado com 48h de antecedência

 

 

Dr Laurent PICOT, 46 years old, born 08/09/1974 in St-Valéry-en-Caux (76, France).

laurent.picot@univ-lr.fr

https://lienss.univ-larochelle.fr/Picot-Laurent-MCF-HDRPhone: 0033546458220

Function: Professor assistant in Biochemistry and Molecular Biology, Pharmacology and Immunology

Institution: La Rochelle University

Lab: UMRi CNRS 7266 Littoral Environement and Societies LIENSs

Team: AMES Molecular Approaches Environment and Health

Doctoral school: ED 618 Euclide la Rochelle University

 

Qualifications

2003 PhD Microbiology, with honours and jury congratulations, University of Rouen, France, “In vitro study of the cytotoxicity of Pseudomonas fluorescens on neurons and glial cells ”. under the supervision of Pr Marc Feuilloley.

2013 Professoral Habilitation (HDR) (PhD supervision) in Biochemistry « Natural molecules from marine and terrestrial biomasses :Extraction, purification, synthesis, pharmacomodulation et and demonstration of pharmacological activities ». La Rochelle University, France.

 

Scientific expertise

Extraction, purification, molecular characterization, pharmacological activity of algae and terrestrial plant molecules.

Biotechnological exploitation of marine and botanical resources in cancer studies.

 

University courses and management

Cell Biology, Cancer, Immunology, Biochemistry, Marine and Terrestrial Pharmacology, Pharmaceutical Chemistry, Biotechnology, Bacteriology, Extraction/Purification/Molecular Characterization Techniques (LC-MS).

 

Scientific activity on the 15/10/2020

1 French patent, 62 publications in international peer-reviewed journals (Biotechnology, Phycology, Biochemistry, Medicinal Chemistry, Pharmacology, Immunology and Bacteriology), 5 book chapters, 52 international conferences, 42 posters at international conferences, h index scopus: 21, Citations: 1332 by 1172 documents.

Supervision of 4 PhD students, rapporteur of 1 Professoral habilitation, members of 6 recruitment committees of university Professor Assistants, 11 PhD committees and juries. Associate Editor of marine Drugs. Reviewer for Nature Microbiology, Marine Drugs, Microalgae Biotechnology, Process Biochemistry, Médecine/Sciences, The Journal of Food Chemistry, The Journal of Food Biochemistry, Gut pathogens, The Journal of Agricultural and Food Chemistry. Head of the Franco-Brazilian network on Natural products https://fb2np.recherche.univ-lr.fr/ and member of several international networks in natural products, chemistry, pharmacology. Coordinator of the Franco-Brazilian Network on Natural Products.

 

5 references

French Patent FR2003712. Bérard J.B., Lefoulon L., Picot L., Ouk T.S., Saad N., Landolt C., Grenier K., Sol V. Use of a polar extract of Skeletonema in a photodynamic therapy. Patent deposited on the 14/04/2020.

 

Gonçalves de Oliveira Junior R., Nicolau E., Bonnet A., Prunier G., Beaugeard L., Joguet N., Thiéry V., Picot L. Carotenoids from Rhodomonas salina induce apoptosis and chemosensitization of human melanoma cells to vemurafenib and dacarbazine. Brazilian Journal of Pharmacognosy 30, 155-168, 2020.

 

Gonçalves de Oliveira Junior R., Marcoult-Freville N., Prunier G., Beaugeard L., Beserra de Alencar Filho E., Simões Mourão E.D., Quintans-Júnior L.J., Guedes da Silva Almeida J., Grougnet R., Picot L. Polymethoxyflavones from Gardenia oudiepe (Rubiaceae) induce cytoskeleton disruption-mediated apoptosis and sensitize BRAF-mutated melanoma cells to chemotherapy. Chemico-Biological Interactions 325, Article 109109, 2020.

 

Haguet Q., Bonnet A., Bérard J.B., Goldberg J., Joguet N., Fleury A., Thiéry V. & Picot L. Antimelanoma activity of Heterocapsa triquetra pigments. Algal research 25, 207-215, 2017.